Good morning friends. A treatment that involves suffocating head lice is quite effective in battling the itchy problem, says a new study.
The non-neurotoxic treatment for head lice has an average of 91.2 per cent treatment success rate after one week, and is safe in humans from six months of age and up.
Benzyl Alcohol Lotion 5percent (known as UlesfiaTM) works by suffocating lice, a method which has been attempted by treating with household items such as mayonnaise, olive oil and petroleum jelly.
Studies have shown that overnight treatments with these home remedies may initially appear to kill lice, but later a ‘resurrection effect’ occurs after rinsing, because lice can resist asphyxiation. This is because of the louse’s ability to presumably close its spiracles, the external entry points to the breathing apparatus, when submerged.
Unlike commonly used asphyxiant remedies, scanning electron microscopy appears to indicate that benzyl alcohol lotion effectively asphyxiates lice by ‘stunning’ the spiracles open, allowing the lotion, comprised of mineral oil and other inactive ingredients, to infiltrate the ‘honeycomb’ respiratory apparatus and kill lice.
The phase III trials were comprised of two multicenter, randomized, double-blind, placebo-controlled trials, conducted among ten geographically diverse sites which assessed the clinical effectiveness and safety of benzyl alcohol lotion. The trails saw the participation of 250 volunteers, who were randomized to treatment or vehicle (lotion but with no active ingredient) groups, treatment was given at day one and day seven, and participants were checked for success at day eight and day 14. On day eight the treatment group had a success rate of 91.2 per cent as an average of both trials, and a 75.6 per cent success rate on day 14; in the vehicle group the success rates were 27.9 per cent and 15.5 per cent respectively.
Study author Terri L Meinking of Global Health Associates of Miami, US, said: “Existing over-the-counter head lice treatments contain neurotoxic pesticides as active ingredients, resulting in potential toxicity and other problems, including lengthy applications, odor, ineffective treatment. Resistance has also become a problem now that lice have had such prolonged exposure to these products.
This leaves practitioners, parents and patients hoping for a safe, non-neurotoxic cure.”
Meinking added: “Since the most popular products have been made readily available, their overuse has caused lice to become resistant just as bacteria have become resistant to many antibiotics.
Because benzyl alcohol lotion kills by suffocation, resistance should not be an issue.” - The Times of India
The findings of the study have appeared in Pediatric Dermatology.